Multiple Sclerosis Brain 1.5T

GE Healthcare – MR Gadopiclenol (VUEWAY®) Protocols

Instructions And Patient Preparation

Instructions: • Exam consists of a high-resolution Sagittal FLAIR sequence to visualize the corpus callosum
• This exam is performed in addition to a brain MRI
• Contrast is used for most adult examinations to evaluate for active demyelination
Position: Supine, head first
Coil: Head, HNU (Head 24 selected if possible)
Landmark: Glabella or chin

Contrast Agent Parameters

Contrast Agent	Dose			Injection Rate
Gadopiclenol (VUEWAY)	0.05 mmol/kg up to a calculated volume of 10 mL			Hand Bolus Perfusion-weighted imaging (PWI), injector at 4-5 mL/sec
Saline Flush	10-20 mL			Hand Flush
Comments	Report agent administered and dose

Imaging Parameters

Scan Description	3PL LOCALIZER	SAGITTAL T1	AXIAL T2 FSFSE	AXIAL T1 3D BRAVO	AXIAL DWI	AXIAL T2* GRE	Pre or Post SAGITTAL T2 FLAIR CUBE	Post AXIAL T1 3D BRAVO	Post CORONAL T1 CUBE
		View Image	View Image		View Image	View Image	View Image	View Image	View Image
Primary Sequence	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Mode	2D	2D	2D	3D BRAVO	2D	2D	3D	3D BRAVO	3D
Pulse Sequence	SSFSE	FSE-XL	FRFSE-XL	BRAVO	SE-EPI	GRE	CUBE	BRAVO	CUBE
Imaging Options	SEQ, EDR, FAST, SS, ARC, TRF	TRF, FAST, ZIP512	FC, TRF, FR, ZIP512	FAST, IRP, ZIP2, ASSET	EPI, DIFF, ASSET	FC	ARC, T2- IRP, ZIP2, EDR	FAST, IRP, ZIP2, ASSET	EDR, ZIP2, ZIP512, FR, ARC

Scan Parameters

Scan Description	3PL LOCALIZER	SAGITTAL T1	AXIAL T2 FSFSE	AXIAL T1 3D BRAVO	AXIAL DWI	AXIAL T2* GRE	Pre or Post SAGITTAL T2 FLAIR CUBE	Post AXIAL T1 3D BRAVO	Post CORONAL T1 CUBE

TE	80	Min-Full	68	―	Min	20	―	―	24
TR	Min	550	3500-4250	―	9000	500	6000	―	550
TI	―	―	―	450	―	600-800	1954 (Fixed with TR)	450	―
Flip Angle	―	―	Auto	13	Auto	10	Auto	13	Auto
ETL	―	4	25	―	―	―	160	―	24
Bandwidth	83.33	20	31	25	125	20	32	25	62
Sat	―	―	Fat	―	Fat	―	Fat	―	Fat

Acquisition Parameters

Scan Description	3PL LOCALIZER	SAGITTAL T1	AXIAL T2 FSFSE	AXIAL T1 3D BRAVO	AXIAL DWI	AXIAL T2* GRE	Pre or Post SAGITTAL T2 FLAIR CUBE	Post AXIAL T1 3D BRAVO	Post CORONAL T1 CUBE

MATRIX freq	256	256	320	256	128	256	256	256	256
MATRIX phase	192	224	256	256	128	224	256	256	256
NEX	1	2	2	1	1	1	1	1	1
Phase FOV	1	1	0.75	―	1	0.75	―	―	―
Freq Direction	Unswap	S/I	A/P	A/P	R/L	A/P	S/I	A/P	S/I
Image Enhance	―	PURE	PURE	PURE	PURE	PURE	PURE	PURE	PURE
FC Direction	―	―	Slice	―	―	Slice	―	―	―
User CV	―	―	―	ACC=2	DIFF Dir-All #T2 images 1 Nex 1 for T2 B1000/1 NEX OPT TE On Dual SE On ACC=2 Ramp Samp=1 Recon 1 Grad OPT 1	―	ACC=2 SL=2	ACC=2	ACC=2

Scanning Range

Scan Description	3PL LOCALIZER	SAGITTAL T1	AXIAL T2 FSFSE	AXIAL T1 3D BRAVO	AXIAL DWI	AXIAL T2* GRE	Pre or Post SAGITTAL T2 FLAIR CUBE	Post AXIAL T1 3D BRAVO	Post CORONAL T1 CUBE

FOV	30	24	22	25	24	24	25	25	24
Slice Thickness	7	5	5	2.4	5	4	1.6	1.2	1.8
Spacing	5	Interleaved	Interleaved	0	1	1	0	0	―
Number of Slices	7-Ax/Sag/Cor	―	24-26	70 locs	24-26	24-26	126	140	112
Scan Time	0:18 sec	2-3 min	~2-3 min	2:30 min	~2-3 min	2:30 min	3-5 min	4 min	2:30 min