Multiple Sclerosis Brain 3T
Siemens Healthineers – MR Gadopiclenol (VUEWAY®) Protocols
Instructions And Patient Preparation
- Instructions
- These sequences done in addition to Routine Adult Brain protocol
- Position
- Supine, head first
- Coil
- 20 channel Head/Neck coil
- Landmark
- Glabella
Contrast Agent Parameters
| Contrast Agent | Dose | Injection Rate | ||||
|---|---|---|---|---|---|---|
| Gadopiclenol (VUEWAY) | 0.05 mmol/kg | Hand Bolus | ||||
| Saline Flush | 10 mL | Hand Bolus | ||||
| Comments | • May use Interpolation & Restore options • May scan postcontrast to allow more time for postcontrast T1 sequences • Report agent administered and dose • Use minimal dose for patients with a GFR <60 mL/sec |
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Imaging Parameters
| Scan Description | AXIAL DWI |
AXIAL T2 |
SAGITTAL T1 MPRAGE |
AXIAL GRE |
Post SAGITTAL FLAIR SPACE |
Post SAGITTAL T1 SPACE |
|---|---|---|---|---|---|---|
| View Image | View Image | View Image | View Image | View Image | View Image | |
| Primary Sequence | epse | tseB | tfl | fl_r | spcir | spcR |
| Dimension | ― | 2D | 3D | 2D | 3D | 3D |
| PAT Mode | GRAPPA | GRAPPA | GRAPPA | GRAPPA | GRAPPA | GRAPPA |
| Acceleration Factor PE | 2 | 2 | 2 | 2 | 2 | 2 |
| Acceleration Factor 3D | ― | ― | 1 | ― | 1 | 2 |
| AutoAlign | Head > Brain | Head > Brain | Head > Brain | Head > Brain | Head > Brain | Head > Brain |
Scan Parameters
| Scan Description | AXIAL DWI |
AXIAL T2 |
T1 MPRAGE |
AXIAL GRE |
Post SAGITTAL FLAIR SPACE |
Post SAGITTAL T1 SPACE |
|---|---|---|---|---|---|---|
| TR | 6700.0 ms | 3000.0 ms | 2200.0 ms | 743.0 ms | 5000 ms | 700 ms |
| TE | 73.00 ms | 101 ms | 2.48 ms | 19.90 ms | 391 ms | 16 ms |
| TI | ― | ― | 904 ms | ― | ― | ― |
| Flip Angle | ― | 90 deg | 8 deg | 20 deg | ― | ― |
| Turbo Factor | ― | 24 | 224 | ― | 284 | 42 |
| Bandwidth | 1502 Hz/Px | 363 Hz/Px | 250 Hz/Px | 220 Hz/Px | 781 Hz/Px | 630 Hz/Px |
| EPI Factor | 128 | ― | ― | ― | ― | ― |
| Fat Saturation Mode | Strong | ― | ― | ― | Strong | None |
| Fat Suppression | Fat Saturation | None | None | None | Fat Saturation | ― |
| Water Suppression | ― | None | None | None | ― | ― |
| Gradient Mode | Fast | Fast | Normal | Fast | Fast | Normal |
| RF Pulse Type | Normal | Fast | Fast | Fast | Normal | Normal |
| Asymmetric Echo | ― | ― | Allowed | Off | ― | ― |
Acquisition Parameters
| Scan Description | AXIAL DWI |
AXIAL T2 |
T1 MPRAGE |
AXIAL GRE |
Post SAGITTAL FLAIR SPACE |
Post SAGITTAL T1 SPACE |
|---|---|---|---|---|---|---|
| Base Resolution | 128 | 320 | 256 | 320 | 256 | 256 |
| Phase Resolution | 100% | ― | 100% | 75% | 100% | 100% |
| Slice Resolution | ― | ― | 100% | ― | 80% | 91% |
| Averages | 1, 2 | 1 | 1 | 1 | 1 | 1.6 |
| Averaging Mode | ― | Short term | Long term | Long term | ― | ― |
| Concatenations | 1 | 2 | 1 | 1 | 1 | 1 |
| b-value | 0 s/mm2 1000 s/mm2 |
― | ― | ― | ― | ― |
| FoV Read | 220 mm | 220 mm | 230 mm | 220 mm | 250 mm | 230 mm |
| FoV Phase | 100% | 100% | 100% | 100% | 100% | 100% |
| Phase Encoding Dir. | A >> P | R >> L | A >> P | A >> P | A >> P | A >> P |
| Phase Oversampling | 0% | 0% | 10% | 0% | 0% | 10% |
| Slice Oversampling | ― | ― | 27% | ― | 0% | 0% |
| Phase Partial Fourier | 6/8 | ― | Off | ― | Allowed | Off |
| Slice Partial Fourier | ― | ― | Off | Off | 6/8 | Off |
| Flow Compensation | ― | No | No | Slice/Read | No | No |
Scanning Range
| Scan Description | AXIAL DWI |
AXIAL T2 |
T1 MPRAGE |
AXIAL GRE |
Post SAGITTAL FLAIR SPACE |
Post SAGITTAL T1 SPACE |
|---|---|---|---|---|---|---|
| Elliptical Filter | Off | Off | Off | On | Off | Off |
| Filter | ― | Distortion Corr.(2D), Prescan Normalize |
Distortion Corr.(2D), Prescan Normalize, Image Filter |
Distortion Corr.(2D), Prescan Normalize, Elliptical filter |
Raw filter, Distortion Corr.(2D), Prescan Normalize |
Raw filter, Distortion Corr.(2D), Prescan Normalize |
| Normalize | Prescan | Off | Off | Off | Off | Off |
| Prescan Normalize | ― | On | On | On | On | On |
| Distance Factor | Off | 0% | 50% | 0% | ― | On |
| Distortion Correction | 5.0 mm | On | On | On | On | 1.0 mm |
| Slice Thickness | 0 | 5.0 mm | 1.0 mm | 5.0 mm | 1.0 mm | ― |
| Slices | 30 Slices | 30 Slices | 176 Slices per Slab | 30 Slices | 176 Slices per Slab | 176 Slices per Slab |
| Acquisition Time | 1:09 min | 1:38 min | 5:38 min | 1:40 min | 3:42 min | 4:12 min |