Pediatric Brain/Orbit Retinoblastoma 3T
Siemens Healthineers – MR Gadopiclenol (VUEWAY®) Protocols
Instructions And Patient Preparation
- Instructions
- Retinoblastoma (RB) orbit and whole-brain imaging.
- Position
- Head first supine
- Coil
- Head 20 or Head 64
- Patient Preparation
- Landmark per department pediatric protocol — pending sign-off.
- Coverage
- Whole Brain coverage — Pre-contrast Sag 3D T1 MPRAGE, TRAN rDWI; Post-contrast TRAN T2 FLAIR, SAG 3D T1 SPACE FS
Orbit coverage — TRAN CISS, COR CISS, TRAN T1 VIBE DIXON PRE & POST
• Superior — Superior margin of midbrain
• Inferior — Mid maxilla
• Anterior — Tip of nose
• Posterior — Mid pons
• Left to Right — Skin to skin
Contrast Agent Parameters
| Contrast Agent | Dose | Injection Rate | Dose Timing Method and Scan Delay | |||||
|---|---|---|---|---|---|---|---|---|
| Gadopiclenol (VUEWAY) | 0.05 mmol/kg | Hand Bolus or Power Injection | Per department pediatric contrast protocol — pending technologist/radiologist sign-off. | |||||
| Comments | • Use minimal dose for patients with a GFR <60 mL/sec • Report agent administered and dose |
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Imaging Parameters
| Scan Description | SAG 3D T1 MPRAGE | TRAN CISS | COR CISS | TRANS rDWI | Tran_T1_VIBE_Dixon | Post Tran_T1_VIBE_Dixon |
Post TRAN T2 FLAIR DR |
Post SAG 3D T1 SPACE FS |
|---|---|---|---|---|---|---|---|---|
| View Image | View Image | View Image | View Image | View Image | View Image | View Image | View Image | |
| Sequence Name | tfl | ci | ci | resolve | fl | fl | tir | spcR |
| Mode | Single Shot | Sequential | Sequential | Interleaved | ― | ― | Interleaved | ― |
| PAT Mode | GRAPPA | ― | ― | ― | None | None | GRAPPA | CS |
| Dimension | 3D | 3D | 3D | 2D | 3D | 3D | 2D | 3D |
| Acceleration Factor PE | 2 | ― | ― | 2 | ― | ― | 2 | ― |
| Acceleration Factor 3D | 1 | ― | ― | ― | ― | ― | ― | ― |
Scan Parameters
| Scan Description | SAG 3D T1 MPRAGE | TRAN CISS | COR CISS | TRANS rDWI | Tran_T1_VIBE_Dixon | Post Tran_T1_VIBE_Dixon |
Post TRAN T2 FLAIR DR |
Post SAG 3D T1 SPACE FS |
|---|---|---|---|---|---|---|---|---|
| TR | 1540.0 ms | 8.34 ms | 8.37 ms | 5160.0 ms | 5.69 ms | 5.69 ms | 10000.0 ms | 900.0 ms |
| TE | 2.76 ms | 3.81 ms | 3.83 ms | 58 ms / 100 ms | 2.46 ms / 3.69 ms | 2.46 ms / 3.69 ms | 106.00 ms | 19.00 ms |
| TI | 900 ms | ― | ― | ― | ― | ― | 2600 ms | ― |
| Flip Angle | 15 deg | 50 deg | 50 deg | 180 deg | 11 deg | 11 deg | 130 deg | ― |
| Turbo Factor | 132 | ― | ― | ― | ― | ― | 12 | 44 |
| Bandwidth | 150 Hz/Px | 454 Hz/Px | 444 Hz/Px | 875 Hz/Px | 740 Hz/Px | 740 Hz/Px | 349 Hz/Px | 434 Hz/Px |
| EPI Factor | ― | ― | ― | 101 | ― | ― | ― | ― |
| Fat Saturation Mode | ― | ― | ― | Strong | ― | ― | Strong | Strong |
| Fat Suppression | Standard | Standard | Standard | Fat Saturation | Dixon | Dixon | Fat Saturation | Fat Saturation |
| Gradient Mode | Normal | Fast | Fast | Fast | Fast | Fast | Fast | Fast |
| RF Pulse Type | Fast | Low SAR | Low SAR | Normal | Fast | Fast | Low SAR | Normal |
| Asymmetric Echo | Allowed | Allowed | Allowed | ― | Weak | Weak | ― | ― |
Acquisition Parameters
| Scan Description | SAG 3D T1 MPRAGE | TRAN CISS | COR CISS | TRANS rDWI | Tran_T1_VIBE_Dixon | Post Tran_T1_VIBE_Dixon |
Post TRAN T2 FLAIR DR |
Post SAG 3D T1 SPACE FS |
|---|---|---|---|---|---|---|---|---|
| Base Resolution | 192 | 256 | 256 | 168 | 160 | 160 | 256 | 256 |
| Phase Resolution | 100 % | 100 % | 100 % | 100 % | 90 % | 90 % | 80 % | 100 % |
| Slice Resolution | 75 % | 100 % | 100 % | ― | 75 % | 75 % | ― | 75 % |
| Averages | 1 | 1 | 1 | ― | 1 | 1 | 1 | 1.0 |
| Concatenations | 1 | ― | ― | 1 | 1 | 1 | 2 | 1 |
| b-value | ― | ― | ― | 0 s/mm²/800 s/mm² | ― | ― | ― | ― |
| FoV Read | 192 mm | 130 mm | 130 mm | 220 mm | 130 mm | 130 mm | 210 mm | 192 mm |
| FoV Phase | 100.0 % | 115.6 % | 115.6 % | 100.0 % | 117.5 % | 117.5 % | 93.8 % | 100.0 % |
| Phase Encoding Dir. | A >> P | R >> L | R >> L | A >> P | R >> L | R >> L | R >> L | A >> P |
| Phase Oversampling | 20 % | 10 % | 5% | 20 % | 15 % | 15 % | 0% | 10 % |
| Slice Oversampling | 10.0 % | 62.5 % | 33.3 % | ― | 100.0 % | 100.0 % | ― | 16.7 % |
| Phase Partial Fourier | Off | Off | Off | Off | Off | Off | Off | Off |
| Slice Partial Fourier | Off | Off | Off | ― | Off | Off | ― | Off |
| Flow Compensation | None | None | None | ― | ― | ― | None | None |
Scanning Range
| Scan Description | SAG 3D T1 MPRAGE | TRAN CISS | COR CISS | TRANS rDWI | Tran_T1_VIBE_Dixon | Post Tran_T1_VIBE_Dixon |
Post TRAN T2 FLAIR DR |
Post SAG 3D T1 SPACE FS |
|---|---|---|---|---|---|---|---|---|
| Elliptical Filter | On | On | On | ― | Off | Off | Off | Off |
| Normalize | Prescan | Prescan | Prescan | Prescan | Prescan | Prescan | Prescan | Prescan |
| Distortion Correction | 2D | 2D | 2D | 2D | 2D | 2D | 2D | 2D |
| Slice Thickness | 1.00 mm | 1.45 mm | 1.45 mm | 4.0 mm | 0.8 mm | 0.8 mm | 4.0 mm | 0.80 mm |
| Distance Factor | 0% | 0% | 0% | 0% | 0% | 0% | 0% | ― |
| Slices | 160 | 64 | 60 | 37 | 120 | 120 | 41 | 192 |
| Acquisition Time | 3:17 min | 7:25 min | 5:28 min | 3:23 min | 3:20 min | 3:20 min | 3:22 min | 4:32 min |