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Comprehensive Brain 3T

Philips Healthcare – MR Gadopiclenol (VUEWAY®) Protocols

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Instructions And Patient Preparation

Instructions
• Contrast is used for assessment of the blood-brain barrier, infection, tumor, and some stroke evaluation
• No patient preparation
Position
Supine, head first
Coil
SENSE-Head-8 channel coil preferred
Landmark
Glabella

Contrast Agent Parameters

Contrast Agent Dose Injection Rate Dose Timing Method and Scan Delay
Gadopiclenol (VUEWAY) 0.05 mmol/kg 5 mL/sec Hand bolus
Saline Flush 20 mL 5 mL/sec Hand bolus
Comments Report agent administered and dose

Info Page

Scan Description Survey DWI AXIAL
T2 TSE		 AXIAL
SWIp		 Survey PCA
for label placement		 AXIAL
3D FFE SPGR T1
Pre		 5 Hour
PERFUSION PRESTO		 AXIAL
3D T1
+Gd		 AXIAL
3D FLAIR
+Gd		 AXIAL
3D T1 TSE
+Gd		 AXIAL
3D FFE SPGR T1 +Gd
    View Image View Image View Image   View Image View Image   View Image View Image View Image
Total scan duration 00:31.4 00:44.8 00:37.4 01:08.0 00:20.6 02:06.0 01:37.7 02:23.8 01:40.8 01:27.0 02:06.0
Rel. SNR 1 1 1 1 1 0 1 2 0 1 0
Act. TR(ms) ― 3732 3120 ― ― ― ― ― ― 600 ―
Act. TE(ms) ― 91 80 ― ― ― ― ― 347 35 ―
Act. TR/TE(ms) 11 / 4.6 ― ― ― 20 / 5.6 25 / 2.6 24 / 35 23 / 2.3 ― ― 25 / 2.6
Act. TR/TI(ms) ― ― ― ― ― ― ― ― 4800 / 1650 ― ―
Act. TR/TE1/delta TE(ms) ― ― ― 31 / 7.2 / 6.2 ― ― ― ― ― ― ―
Dyn. scan time ― ― ― ― ― ― 00:01.9 ― ― ― ―
Time to k0 ― ― ― ― ― ― 0.954 ― ― ― ―
ACQ matrix M x P 268 x 128 152 x 122 404 x 238 288 x 240 256 x 128 268 x 267 100 x 100 232 x 232 268 x 268 244 x 244 268 x 267
ACQ voxel MPS (mm) 0.97 / 2.03 / 10.0 1.51 / 1.88 / 4.00 0.57 / 0.76 / 5.00 0.80 / 0.80 / 2.50 1.17 / 2.34 / 50.0 0.90 / 0.90 / 1.80 2.00 / 2.00 / 3.00 0.99 / 0.99 / 3.00 0.90 / 0.90 / 1.80 0.90 / 0.90 / 1.80 0.90 / 0.90 / 1.80
REC voxel MPS (mm) 0.90 / 0.90 / 10.0 1.20 / 1.20 / 4.00 0.45 / 0.45 / 5.00 0.45 / 0.45 / 1.25 1.17 / 1.17 / 50.0 0.71 / 0.71 / 0.90 1.79 / 1.79 / 3.00 0.72 / 0.72 / 3.00 0.83 / 0.83 / 0.90 0.38 / 0.38 / 0.90 0.71 / 0.71 / 0.90
Scan percentage (%) 48 80 75 100 50 100 100 100 100 100 100
Packages ― 1 2 ― ― ― ― ― ― ― ―
Min. slice gap (mm) ― 0 5 ― ― ― ― ― ― ― ―
EPIfactor ― 41 ― ― ― ― ― ― ― ― ―
TFE shots 2 ― ― ― ― ― ― ― ― ― ―
TFE dur. shot / acq (ms) 1162.5 / 704.0 ― ― ― ― ― ― ― ― ― ―
TFE shot interval (ms) 1162.5 ― ― ― ― ― ― ― ― ― ―
Min. TI delay 397.4 ― ― ― ― ― ― ― ― ― ―
Act.slicegap (mm) ― ― ― -1.3 ― -0.9 0 0 -0.9 -0.9 -0.9
Act. WFS (pix) / BW (Hz) 3.101 / 140.1 ― ― 1.701 / 255.3 1.935 / 224.5 1.201 / 361.6 7.920 / 54.8 4.199 / 103.4 ― ― 1.201 / 361.6
BW in EPI freq. dir. (Hz) ― ― ― ― ― ― 1904.6 ― ― ― ―
Min. WFS (pix) / Max. BW (Hz) 0.587 / 740.3 ― ― 0.570 / 761.4 0.872 / 498.2 0.512 / 848.0 7.919 / 54.8 0.459 / 945.2 ― ― 0.512 / 848.0
Min. TR/TE(ms) 9.4 / 3.7 ― ― ― 9.7 / 5.6 15 / 2.6 ― 20 / 1.8 ― ― 15 / 2.6
Min. TR/TE1/delta TE(ms) ― ― ― 29 / 5.2 / 5.7 ― ― ― ― ― ― ―
WFS (pix) / BW (Hz) ― 15.266 / 28.4 2.555 / 170.0 ― ― ― ― ― 0.512 / 848.0 1.640 / 264.7 ―
TSE es / shot(ms) ― ― 9.4 / 151 ― ― ― ― ― 3.6 / 662 7.0 / 174 ―
TEeff / TEequiv(ms) ― ― 80 / 72 ― ― ― ― ― 347 / 144 35 / 19 ―
Min. TR(ms) ― ― 3120 ― ― ― ― ― ― 328 ―
Min. TR/TI(ms) ― ― ― ― ― ― ― ― 2462 / 50 ― ―
BW in EPI freq. dir. (Hz) ― 1447.8 ― ― ― ― ― ― ― ― ―
SPIR offset act./default (Hz) ― 220 [220] ― ― ― ― ― ― ― ― ―
ES-FFE: added M area ― ― ― ― ― ― -23.5 ― ― ― ―
ES-FFE: added P area ― ― ― ― ― ― -23.5 ― ― ― ―
ES-FFE: added S area ― ― ― ― ― ― -23.5 ― ― ― ―
Local torso SAR < 12 % < 32 % < 100 % < 8 % < 4 % < 60 % < 2 % < 80 % < 16 % < 20 % < 60 %
Whole body SAR / level < 0.4 W/kg / normal < 1.0 W/kg / normal < 3.2 W/kg / 1st level < 0.3 W/kg / normal < 0.1 W/kg / normal < 1.9 W/kg / normal < 0.1 W/kg / normal < 2.6 W/kg / 1st level < 0.5 W/kg / normal < 0.6 W/kg / normal < 1.9 W/kg / normal
SED 0.0 kJ/kg 0.0 kJ/kg < 0.1 kJ/kg 0.0 kJ/kg 0.0 kJ/kg < 0.2 kJ/kg 0.0 kJ/kg < 0.4 kJ/kg < 0.1 kJ/kg < 0.1 kJ/kg < 0.2 kJ/kg
Coil Power 0% 0% 1% 0% 0% 0% 0% 0% 0% 0% 0%
Max B1+rms 0.79 uT 1.30 uT 2.29 uT 0.65 uT 0.43 uT 1.77 uT 0.31 uT 2.04 uT 0.98 uT 1.02 uT 1.77 uT
PNS / level 53 % / normal 80 % / 1st level 62 % / normal 78 % / normal 15 % / normal 77 % / normal 96 % / 1st level 66 % / normal 68 % / normal 73 % / normal 77 % / normal
dB/dt 46.6 T/s 105.0 T/s 81.5 T/s 61.9 T/s 16.1 T/s 88.5 T/s 102.6 T/s 87.9 T/s 79.5 T/s 84.4 T/s 88.5 T/s
Sound Pressure Level (dB) 10.4 14.5 5 8 -10.7 8.5 19 6.3 12.2 8.1 8.5
Boil-off (hPa/h) ― 12.3 2 5.8 ― 3.4 27.9 2.5 1.3 1.7 3.4
Max Boil-off (hPa/h) ― 12.3 2 5.8 ― 3.4 27.9 2.5 10 2.7 3.4
Boil-off (hPa) ― 0.2 0 0.1 ― 0.1 0.8 0.1 0 0 0.1

Geometry

Scan Description Survey DWI AXIAL
T2 TSE		 AXIAL
SWIp		 Survey PCA
for label placement		 AXIAL
3D FFE SPGR T1
Pre		 5 Hour
PERFUSION PRESTO		 AXIAL
3D T1
+Gd		 AXIAL
3D FLAIR
+Gd		 AXIAL
3D T1 TSE
+Gd		 AXIAL
3D FFE SPGR T1 +Gd
                       
Nucleus ― H1 H1 H1 ― H1 H1 H1 H1 H1 H1
SmartSelect ― yes yes yes ― yes yes yes yes yes yes
Coil 1 (exclude) ― None None None ― None None None None None None
Uniformity Classic CLEAR CLEAR CLEAR CLEAR CLEAR CLEAR CLEAR CLEAR CLEAR CLEAR
FOV AP (mm) 260 230 230 230 300 240 200 230 240 220 240
FOV FH (mm) 260 149 150 138 300 169 96 96 169 169 169
FOV RL (mm) ― 230 181 192 115 240 200 230 240 220 240
stack RL (mm) 50 ― ― ― ― ― ― ― ― ― ―
ACQ voxel size AP (mm) 2 1.9 0.6 0.8 2.3 0.9 2 1 0.9 0.9 0.9
ACQ voxel size FH (mm) 1 ― ― 2.5 1.2 1.8 3 3 1.8 1.8 1.8
ACQ voxel size RL (mm) ― 1.5 0.8 0.8 ― 0.9 2 1 0.9 0.9 0.9
Slice thickness (mm) 10 4 5 ― 50 ― ― ― ― ― ―
Recon voxel size AP (mm) 0.9 1.2 0.4 0.4 1.2 0.7 1.8 0.7 0.8 0.4 0.7
Recon voxel size FH (mm) 0.9 ― ― 1.3 1.2 0.9 3 3 0.9 0.9 0.9
Recon voxel size RL (mm) ― 1.2 0.4 0.4 ― 0.7 1.8 0.7 0.8 0.4 0.7
Fold-over suppression no no no no no no no no no no no
Slice oversampling ― ― ― default ― default default default default user defined default
      oversample factor ― ― ― ― ― ― ― ― ― 1.3 ―
ENCASE enable ― ― ― no ― no no no ― ― no
RF select. FOS ― ― ― ― ― ― ― ― no no ―
Reconstruction matrix 288 192 512 512 256 336 112 320 288 576 336
SENSE no yes no no no no yes yes no no no
      P reduction (AP) ― 3 ― ― ― ― ― ― ― ― ―
      P reduction (RL) ― ― ― ― ― ― 2 2.3 ― ― ―
      S reduction (FH) ― ― ― ― ― ― 1 1 ― ― ―
MB SENSE ― no ― ― ― ― ― ― ― ― ―
CS-SENSE ― no yes yes ― yes no no yes yes yes
      reduction ― ― 3 7 ― 7 ― ― 12 8.5 7
      denoising ― ― system default system default ― system default ― ― system default system default system default
k-t Acceleration ― no no no ― no no no no no no
Stacks 3 1 1 1 1 1 1 1 1 1 1
      current A ― ― ― ― ― ― ― ― ― ―
      type parallel parallel parallel ― parallel ― ― ― ― ― ―
      slices 3 30 30 110 2 188 32 32 188 188 188
      slice gap user defined user defined user defined ― user defined ― ― ― ― ― ―
      gap (mm) 10 1 0 ― 15 ― ― ― ― ― ―
      slice orientation sagittal transverse transverse transverse sagittal transverse transverse transverse transverse transverse transverse
      fold-over direction AP AP RL RL AP RL RL RL RL RL RL
      fat shift direction F P P P F P L P P P P
Minimum number of packages ― 1 1 ― ― ― ― ― ― ― ―
Slice scan order default default default ― default ― ― ― ― ― ―
Stack scan order ascend ― ― ― ― ― ― ― ― ― ―
Stack sort order no ― ― ― ― ― ― ― ― ― ―
Multi-chunk ― ― ― no ― no no no no no no
O-MAR ― ― no ― ― ― ― ― no no ―
Large table movement ― no no no ― no no no no no no
Plan Align no no no no no no no no no no no
REST slabs 0 0 1 0 0 1 0 1 0 0 1
      type ― ― parallel ― ― parallel ― free ― ― parallel
      orientation ― ― ― ― ― ― ― transverse ― ― ―
      thickness (mm) ― ― 60 ― ― 60 ― 60 ― ― 60
      position ― ― feet ― ― feet ― ― ― ― feet
      gap ― ― default ― ― default ― ― ― ― default
      power ― ― 1 ― ― 1 ― 1 ― ― 1
Interactive positioning ― no no no ― no no no no no no
Allow table movement ― no no no ― no no no no no no
Patient position ― head first head first head first ― head first head first head first head first head first head first
Patient body position ― head first head first head first ― head first head first head first head first head first head first
Patient orientation ― supine supine supine ― supine supine supine supine supine supine
Patient body orientation ― supine supine supine ― supine supine supine supine supine supine

Contrast

Scan Description Survey DWI AXIALT2 TSE AXIALSWIp Survey PCAfor label placement AXIAL3D FFE SPGR T1Pre 5 HourPERFUSION PRESTO AXIAL3D T1 +Gd AXIAL3D FLAIR +Gd AXIAL3D T1 TSE +Gd AXIAL3D FFE SPGR T1 +Gd
Scan type &#8213 Imaging Imaging Imaging &#8213 Imaging Imaging Imaging Imaging Imaging
Scan mode M2D MS MS 3D M2D 3D 3D 3D 3D 3D
Modified SE &#8213 no no &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 no
3D non-selective &#8213 &#8213 &#8213 no &#8213 no no no &#8213 &#8213
Contrast enhancement T1 &#8213 &#8213 T1 T1 T1 T1 T1 &#8213 &#8213
Acquisition mode &#8213 cartesian cartesian cartesian &#8213 cartesian cartesian cartesian cartesian cartesian
Fast Imaging mode TFE EPI TSE none none none EPI none TSE TSE
3D VIEW &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 Brain FLAIR Brain T1
TFE factor 64 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213
TSE factor &#8213 &#8213 16 &#8213 &#8213 &#8213 &#8213 &#8213 178 20
EPI factor &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 25 &#8213 &#8213 &#8213
EPI direction &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 Y &#8213 &#8213 &#8213
Echoes 1 1 1 4 1 1 1 1 1 1
TE&gt;TR shift &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 1 &#8213 &#8213 &#8213
TE in-phase shortest user defined user defined shortest shortest shortest in-phase shortest shortest
(ms) 4.6 &#8213 80 7.2 &#8213 &#8213 &#8213 2.3 &#8213 &#8213 &#8213
Flip angle (deg) 15 90 90 17 15 30 7 30 &#8213 90
Refocusing control &#8213 &#8213 constant &#8213 &#8213 &#8213 &#8213 &#8213 constant constant
TR user defined shortest range user defined user defined user defined shortest user defined user defined user defined
Halfscan no yes no no no no no no no no
Water-fat shift user defined minimum maximum user defined maximum user defined maximum maximum maximum maximum
IR delay(ms) &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 1650 &#8213
RF Shims fixed fixed adaptive fixed fixed adaptive fixed adaptive fixed fixed
Shim default auto default auto default auto default auto default auto
mDIXON no no no no no no no no no no
Fat suppression no SPIR no no no no no no SPIR SPAIR
Grad Rev Fat suppr &#8213 yes no &#8213 &#8213 &#8213 &#8213 &#8213 no no
Water suppression no no no no no no no no no no
BB pulse &#8213 no no &#8213 &#8213 &#8213 &#8213 &#8213 no no
TFE prepulse invert &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213
MTC no no no no no no no no no no
APT &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213
Saturation B1 rms (uT) &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213
Saturation duration (s) &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213
T2prep &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 yes no
APT &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213 &#8213
Custom prepulse &#8213 no no no &#8213 no no no no no
MDME &#8213 no no no &#8213 no no no no no
Diffusion mode &#8213 DWI no no &#8213 no no no no no
T1 mapping &#8213 no no no &#8213 no no no no no
Transmit channels &#8213 both both both &#8213 both both both both both
SAR mode high high high high high high high high high high
B1 mode default default default default user defined default default default default default
SAR allow first level yes yes yes yes yes yes yes yes yes yes
Patient pregnancy &#8213 no no no &#8213 no no no no no
Patient WB SAR [W/kg] &#8213 — — — &#8213 — — — — —
Patient Head SAR [W/kg] &#8213 — — — &#8213 — — — — —
Patient max. dB/dt [T/s] &#8213 — — — &#8213 — — — — —
Max slewrate [T/m/s] &#8213 — — — &#8213 — — — — —
Max. B1+rms [uT] &#8213 — — — &#8213 — — — — —
PNS mode low high high moderate low high high high moderate moderate
Gradient mode default maximum maximum maximum regular maximum maximum maximum maximum maximum
SofTone mode no no no no no no no no no no

Motion

Scan Description Survey DWI AXIAL
T2 TSE		 AXIAL
SWIp		 Survey PCA
for label placement		 AXIAL
3D FFE SPGR T1
Pre		 5 Hour
PERFUSION PRESTO		 AXIAL
3D T1
+Gd		 AXIAL
3D FLAIR
+Gd		 AXIAL
3D T1 TSE
+Gd		 AXIAL
3D FFE SPGR T1 +Gd
                       
Cardiac synchronization no no no no no no no no no no no
Heart rate >250 bpm ― no no no ― no no no no no no
Respiratory compensation no no no no no no no no no no no
Navigator respiratory comp ― no no no ― no no no no no no
Flow compensation no no no yes yes no no no no no no
Temporal slice spacing ― default default ― ― ― ― ― ― ― ―
fMRI echo stabilisation ― ― ― no ― no no no ― ― no
Motion smoothing ― ― no ― ― ― ― ― no no ―
NSA 1 1 1 1 1 1 1 2 1 1 1
SMART ― ― ― ― ― ― ― no ― ― ―
MRE enable no no no no no no no no no no no

Dynamic Angio

Scan Description Survey DWI AXIAL
T2 TSE		 AXIAL
SWIp		 Survey PCA
for label placement		 AXIAL
3D FFE SPGR T1
Pre		 5 Hour
PERFUSION PRESTO		 AXIAL
3D T1
+Gd		 AXIAL
3D FLAIR
+Gd		 AXIAL
3D T1 TSE
+Gd		 AXIAL
3D FFE SPGR T1 +Gd
                       
Angio / Contrast enh. no ― ― no phase contrast no no no ― ― no
PC flow directions ― ― ― ― RL-AP-FH ― ― ― ― ― ―
      uniform velocity ― ― ― ― yes ― ― ― ― ― ―
PC velocity (cm/s) ― ― ― ― 50 ― ― ― ― ― ―
Quantitative flow ― ― ― no ― no no no ― ― no
CENTRA ― ― ― ― ― ― ― ― no no ―
Manual start no no no no no no yes no no no no
Dynamic study no no no no no no individual no no no no
      dyn scans ― ― ― ― ― ― 50 ― ― ― ―
      dyn scan times ― ― ― ― ― ― shortest ― ― ― ―
      fov time mode ― ― ― ― ― ― default ― ― ― ―
      dummy scans ― ― ― ― ― ― 0 ― ― ― ―
      immediate subtraction ― ― ― ― ― ― no ― ― ― ―
      fast next scan ― ― ― ― ― ― no ― ― ― ―
      synch. ext. device ― ― ― ― ― ― no ― ― ― ―
      dyn stabilization ― ― ― ― ― ― no ― ― ― ―
      prospect. motion corr. ― ― ― ― ― ― no ― ― ― ―
Keyhole ― ― ― ― ― ― no ― ― ― ―
Arterial Spin labeling ― no no no ― no no no no no no

Post Processing

Scan Description Survey DWI AXIAL
T2 TSE		 AXIAL
SWIp		 Survey PCA
for label placement		 AXIAL
3D FFE SPGR T1
Pre		 5 Hour
PERFUSION PRESTO		 AXIAL
3D T1
+Gd		 AXIAL
3D FLAIR
+Gd		 AXIAL
3D T1 TSE
+Gd		 AXIAL
3D FFE SPGR T1 +Gd
                       
Preparation phases auto auto auto auto auto auto auto auto auto auto auto
Interactive F0 no no no no no no no no no no no
Quick Survey default default default default default default default default default default default
SmartPlan survey ― no no no ― no no no no no no
B0 field map ― no no no ― no no no no no no
B1 field map ― no no no ― no no no no no no
MIP/MPR no no no no no no no no no no no
SWIp ― ― ― yes ― no no no ― ― no
Images M, no, no, no M, (3) no M, (3) no SW-M, SW-P, (2) no M, no, no, no M, (3) no M, (3) no M, (3) no M, (3) no M, (3) no M, (3) no
Autoview image M M M ― M M M M M M M
Calculated images no, no, no, no (4) no (4) no ― no, no, no, no (4) no (4) no (4) no Grey matter (4) no (4) no
Reference tissue White matter Grey matter Grey matter White matter Grey matter White matter White matter White matter No White matter White matter
Recon compression No No No No No No No No ― No No
Preset window contrast soft soft soft soft soft soft soft soft soft soft soft
Reconstruction mode immediate real time real time real time immediate immediate real time immediate real time immediate immediate
 reuse memory ― ― ― ― ― ― no ― ― ― ―
Save raw data no no no no no no no no no no no
Hardcopy protocol no no no no no no no no no no no
Image filter system default system default system default system default system default system default system default system default system default system default system default
Uniformity correction no no no no no no no yes no no
Geometry correction default default default default default default default default default default default
Elliptical k-space shutter ― ― ― default ― no default default default default no
EPI geometry correction ― no ― ― ― ― ― ― ― ― ―
ADC correction ― no ― ― ― ― ― ― ― ― ―
PCA Local Phase Corr. ― ― ― ― yes ― ― ― ― ― ―
Free rotatable ― no no no ― no no no no no no