Gynecologic Cancer Staging 3.0T

GE Healthcare – MR Gadopiclenol (VUEWAY®) Protocols

Instructions: • Small FOV: Centered on uterus
• Large FOV: Renal vein level to symphysis
• Oblique axis refers to the tumor axis in the uterus (varies for endometrium vs cervix)
• Vaginal gel: 30-60 mL
• For metal artifacts consider 1.5T, reduced FOV multishot DWI, changing readout direction
Common Indications: Staging endometrial, cervical, vaginal, vulvar, ovarian/adnexal malignancy
Position: Supine
Coil: 32 channel Torso, GEMS Body array, or Air coil
Landmark: Iliac Crest
Gadopiclenol (VUEWAY): 0.05 mmol/kg up to a calculated volume of 10 mL
Saline Flush: 50 mL
Comments: —

Contrast Agents	Dose			Injection Rate		Dose Timing Method and Scan Delay
Gadopiclenol (VUEWAY)	0.05 mmol/kg up to a calculated volume of 10 mL			2 mL/sec		Pre – Axial Late Arterial – Sagittal T1 90-120 sec – Axial T1 3-5 min post
Saline Flush	50 mL			2 mL/sec		Immediately following gadolinium
Comments	—	Above kidneys to below symphysis	—	—	Breath hold Pre, Late Arterial, 3-5 min	Breath hold 90-120 sec postcontrast injection	Axial DWI	Optional: For ovaries

Scan Description	3PL LOCALIZER SSFSE	CORONAL SSFSE	SAGITTAL T2	AXIAL or OBLIQUE AXIAL T2	AXIAL T1 LAVA-Flex	SAGITTAL T1 LAVA-Flex	AXIAL DWI	CORONAL T2
			View Image	View Image	View Image	View Image		View Image
Mode	2D	2D	2D	2D	3D	3D	2D	2D
Pulse Sequence	SSFSE	SSFSE	FRFSE-XL	FRFSE-XL	LAVA-Flex	LAVA-Flex	EPI-DIFF	FRFSE-XL
Imaging Options	EDR, SEQ, SS, ARC, FAST	ZIP512, FAST	FC, TRf, FAST, FR	FC, TRf, FAST, FR, NPW	EDR, ZIP512, ZIP2, ARC	EDR, ZIP512, ZIP2, ARC	EPI, DIFF, ASSET, 1 Shot	FC, TRf, FAST, FR

Scan Description	3PL LOCALIZER SSFSE	CORONAL SSFSE	SAGITTAL T2	AXIAL or OBLIQUE AXIAL T2	AXIAL T1 LAVA-Flex	SAGITTAL T1 LAVA-Flex	AXIAL DWI	CORONAL T2

TE	90	90	103	103	Def	Def	Min	103
TR	Min	Min	3400	3400	Def	Def	6000	3400
Flip Angle	—	—	—	—	15	15	—	—
ETL	—	—	21	21	—	—	—	21
Bandwidth	83	83	62	62	142	142	—	62
SAT	—	—	Sat Scr Ant Sat	Sat Scr Ant Sat	—	—	—	—

Scan Description	3PL LOCALIZER SSFSE	CORONAL SSFSE	SAGITTAL T2	AXIAL or OBLIQUE AXIAL T2	AXIAL T1 LAVA-Flex	SAGITTAL T1 LAVA-Flex	AXIAL DWI	CORONAL T2

MATRIX freq	288	256	320	320	264	264	192	320
MATRIX phase	192	224	224	224	224	224	192	224
NEX	1	1	2	2	1	1	—	2
Phase FOV	1	1	1	1	1	1	1	1
Freq Direction	—	S/I	S/I	A/P	R/L	R/L	S/I	S/I
Accel	Ph 2	—	—	—	—	—	—	—
User CV	1, 240, 1	1, 240, 1	—	—	Turbo 1	Turbo 1	Ramp samp 1 Flair Inv 0 Grad opt 1	—
Other	—	—	—	—	Precontrast: Water, Fat, In Phase, Out Phase acquired	—	DWI b val 0-50 6 nex Diff Dir ALL b val 400-1000 6 nex Opt TE On	—

Scan Description	3PL LOCALIZER SSFSE	CORONAL SSFSE	SAGITTAL T2	AXIAL or OBLIQUE AXIAL T2	AXIAL T1 LAVA-Flex	SAGITTAL T1 LAVA-Flex	AXIAL DWI	CORONAL T2

FOV	48	36	28	28	32	32	30	28
Slice Thickness	8	5	2.9	2.9	3.2	3.2	4	2.9
Spacing	0	1	0.3	0.3	0	0	0.5	0.3
Number of Slices	21 Slices	Slices PRN	15 Slices/acq	15 Slices/acq	104 Locs	104 Locs	30 Slices	15 Slices/acq
Approx. Scan Time	0:19	0:18/acq	4:00 ±	4:00 ±	0:24	0:24	2:26	4:00 ±