Multiple Sclerosis Brain 3T
Philips Healthcare – MR Gadopiclenol (VUEWAY®) Protocols
Instructions And Patient Preparation
- Instructions
- • Change patient into hospital issued gown and pants
• 18- to 22-gauge IV access
• Sagittal FLAIR using thin 3 mm slices - Position
- Supine, head first
- Coil
- SENSE-Head-8 channel coil preferred. If a cervical spine MS evaluation is also done, then a 16 channel neurovascular coil is preferred
- Landmark
- Glabella
Contrast Agent Parameters
| Contrast Agent | Dose | Injection Rate | ||||||
|---|---|---|---|---|---|---|---|---|
| Gadopiclenol (VUEWAY) | 0.05 mmol/kg | 1-2 mL/sec | ||||||
| Saline Flush | 10-20 mL | 1-2 mL/sec | ||||||
| Comments | • 3D scan optional postcontrast – reformat orthogonal planes as appropriate • Do 3D T2 FLAIR precontrast and reformat in orthogonal planes • T2 postcontrast done to provide increased delay between contrast and Axial T1 postcontrast • Postcontrast at least 1 plane should be similar sequence pre- and postcontrast |
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Info Page
| Scan Description | Survey Brain |
AXIAL T1 +C |
AXIAL T2 Fat Sat |
AXIAL T2 FLAIR +C |
Source DTI |
SAGITTAL 3D T1 |
SAGITTAL 3D T2 FLAIR |
SAGITTAL 3D T1 +C |
|---|---|---|---|---|---|---|---|---|
| View Image | View Image | View Image | View Image | View Image | View Image | View Image | View Image | |
| Total scan duration | 00:18.9 | 02:16.8 | 01:45.0 | 02:45.0 | 02:00.8 | 02:17.8 | 03:44.0 | 02:17.8 |
| Rel. SNR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Act. TR (ms) | — | 462 | 3000 | — | 4923 | — | — | — |
| Act. TR/TI (ms) | — | — | — | 11000 / 2800 | — | — | 8000 / 2400 | — |
| Act. TE (ms) | — | 10 | 80 | 120 | 68 | — | 267 | — |
| Act. TR/TE (ms) | 15 / 3.2 | — | — | — | — | 7.8 / 3.5 | — | 7.8 / 3.5 |
| ACQ matrix M x P | 124 x 84 | 276 x 180 | 224 x 175 | 316 x 175 | 112 x 112 | 220 x 220 | 240 x 240 | 220 x 220 |
| ACQ voxel MPS (mm) | 2.02 / 2.98 / 10.0 | 0.80 / 0.99 / 3.00 | 0.98 / 1.10 / 3.00 | 0.70 / 1.10 / 3.00 | 2.00 / 2.00 / 3.00 | 1.09 / 1.09 / 1.00 | 1.00 / 1.00 / 2.00 | 1.09 / 1.09 / 1.00 |
| REC voxel MPS (mm) | 1.74 / 1.74 / 10.0 | 0.43 / 0.43 / 3.00 | 0.46 / 0.46 / 3.00 | 0.43 / 0.43 / 3.00 | 1.00 / 1.00 / 3.00 | 0.94 / 0.94 / 1.00 | 0.50 / 0.50 / 1.00 | 0.94 / 0.94 / 1.00 |
| Scan percentage (%) | 68 | 80 | 89 | 63 | 100 | 100 | 100 | 100 |
| Act. slice gap (mm) | — | — | — | — | — | 0 | -1 | 0 |
| Packages | — | 2 | 5 | 3 | 1 | — | — | — |
| Min. slice gap (mm) | — | 0 | 0 | 0.6 | 0 | — | — | — |
| Optimal slices | — | 25 | 10 | 34 | — | — | — | — |
| Max.slices | — | — | — | 51 | — | — | — | — |
| EPI factor | — | — | — | — | 45 | — | — | — |
| TFE shots | 2 | — | — | — | — | 68 | — | 68 |
| TFE dur. shot / acq (ms) | 701.6 / 630.0 | — | — | — | — | 1752.0 / 1711.3 | — | 1752.0 / 1711.3 |
| TFE shot interval (ms) | 701.6 | — | — | — | — | — | — | — |
| Min. TI delay | 375.1 | — | — | — | — | 890.3 | — | 890.3 |
| Act. WFS (pix) / BW (Hz) | 1.125 / 386.2 | — | — | — | — | 2.080 / 208.9 | — | 2.080 / 208.9 |
| Min. WFS (pix) / Max. BW (Hz) | 0.509 / 854.3 | — | — | — | — | 0.482 / 901.9 | — | 0.482 / 901.9 |
| WFS (pix) / BW (Hz) | — | 2.676 / 162.3 | 1.619 / 268.3 | 1.999 / 217.3 | 13.193 / 32.9 | — | 0.475 / 913.7 | — |
| BW in EPI freq. dir. (Hz) | — | — | — | — | 1844.5 | — | — | — |
| Full flow comp. | — | no | — | — | — | — | no | — |
| TSE es / shot (ms) | — | — | 10.0 / 160 | 10.9 / 229 | — | — | 4.3 / 503 | — |
| TEeff / TEequiv (ms) | — | — | 80 / 72 | 120 / 106 | — | — | 267 / 128 | — |
| Min. TR (ms) | — | 462 | 2865 | — | — | — | — | — |
| Min. TR/TI (ms) | — | — | — | 7470 / 50 | — | — | 2912 / 50 | — |
| Min. TR/TE (ms) | 6.3 / 3.2 | — | — | — | — | — | — | — |
| SPAIR TR (ms) | — | — | — | — | — | — | 8000 | — |
| SPAIR inv. delay (ms) | — | — | — | — | — | — | 220 | — |
| SPAIR offset act./default (Hz) | — | — | — | — | — | — | 100 [220] | — |
| Local extremities SAR | — | < 72 % | < 36 % | < 21 % | — | < 3 % | < 2 % | < 3 % |
| Local torso SAR | < 31 % | — | — | — | < 83 % | — | — | — |
| Whole body SAR / level | < 0.7 W/kg / normal | < 0.2 W/kg / normal | < 0.1 W/kg / normal | < 0.1 W/kg / normal | < 1.9 W/kg / normal | 0.0 W/kg / normal | 0.0 W/kg / normal | 0.0 W/kg / normal |
| SED | 0.0 kJ/kg | 0.0 kJ/kg | 0.0 kJ/kg | 0.0 kJ/kg | < 0.2 kJ/kg | 0.0 kJ/kg | 0.0 kJ/kg | 0.0 kJ/kg |
| Coil Power | — | — | — | — | 39% | — | — | — |
| Max B1+rms | 0.90 uT | 4.23 uT | 2.99 uT | 2.38 uT | 1.47 uT | 0.87 uT | 0.64 uT | 0.87 uT |
| PNS / level | 17 % / normal | 74 % / normal | 24 % / normal | 20 % / normal | 86 % / 1st level | 51 % / normal | 65 % / normal | 51 % / normal |
| dB/dt | 15.4 T/s | 66.4 T/s | 18.9 T/s | 18.9 T/s | 112.7 T/s | 49.9 T/s | 96.9 T/s | 49.9 T/s |
| Sound Pressure Level (dB) | 2.7 | 23 | 5 | 4.8 | 21.9 | 18.8 | 25.5 | 18.8 |
Geometry
| Scan Description | Survey Brain |
AXIAL T1 +C |
AXIAL T2 Fat Sat |
AXIAL T2 FLAIR +C |
Source DTI |
SAGITTAL 3D T1 |
SAGITTAL 3D T2 FLAIR |
SAGITTAL 3D T1 +C |
|---|---|---|---|---|---|---|---|---|
| SmartSelect | yes | yes | yes | yes | yes | yes | yes | yes |
| Coil 1 (exclude) | — | None | None | None | None | None | None | None |
| Uniformity | — | CLEAR | CLEAR | CLEAR | CLEAR | CLEAR | CLEAR | CLEAR |
| FOV AP (mm) | 250 | 220 | 220 | 220 | 224 | 240 | 240 | 240 |
| FOV (mm) | (3) 50, (17) 10 | — | — | — | — | — | — | — |
| FOV FH (mm) | 250 | 150 | 150 | 150 | 150 | 240 | 240 | 240 |
| FOV RL (mm) | — | 179 | 193 | 193 | 224 | 180 | 180 | 180 |
| ACQ voxel size AP (mm) | 2 | 0.8 | 1 | 0.7 | 2 | 1 | 1 | 1 |
| ACQ voxel size FH (mm) | 2 | — | — | — | — | 1 | 1 | 1 |
| ACQ voxel size RL (mm) | — | 1 | 1 | 0.9 | 2 | 1 | 2 | 1 |
| Slice thickness (mm) | 10 | 3 | 3 | 3 | 3 | — | — | — |
| Bar orientation | RL | — | — | — | — | — | — | — |
| VOI orientation | transverse | — | — | — | — | — | — | — |
| VOI size AP (mm) | 30 | — | — | — | — | — | — | — |
| VOI size RL (mm) | 30 | — | — | — | — | — | — | — |
| VOI size FH (mm) | 30 | — | — | — | — | — | — | — |
| Recon voxel size AP (mm) | 1.7 | 0.4 | 0.5 | 0.4 | 1 | 0.9 | 0.5 | 0.9 |
| Recon voxel size FH (mm) | 1.7 | — | — | — | — | 0.9 | 0.5 | 0.9 |
| Recon voxel size RL (mm) | — | 0.4 | 0.5 | 0.4 | 1 | 1 | 1 | 1 |
| Fold-over suppression | no | no | no | no | no | no | no | no |
| P (mm) | 50 | — | — | — | — | — | — | — |
| A (mm) | 50 | — | — | — | — | — | — | — |
| Slice oversampling | — | — | — | — | — | default | user defined | default |
| oversample factor | — | — | — | — | — | — | 1 | — |
| ENCASE enable | — | — | — | — | — | no | — | no |
| Reconstruction matrix | 144 | 512 | 480 | 512 | 224 | 256 | 480 | 256 |
| SENSE | no | no | no | no | yes | no | no | no |
| P reduction (AP) | — | — | — | — | 2.5 | — | — | — |
| MB SENSE | — | — | — | — | no | — | — | — |
| CS-SENSE | no | yes | yes | yes | no | yes | yes | yes |
| reduction | — | 2.5 | 2 | 2.2 | — | 3 | 6 | 3 |
| denoising | — | system default | system default | system default | — | system default | system default | system default |
| k-t Acceleration | no | no | no | no | no | no | no | no |
| Stacks | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| type | (20) parallel | parallel | parallel | parallel | parallel | — | — | — |
| Slices | (3) 3, (17) 1 | 50 | 50 | 50 | 50 | 180 | 180 | 180 |
| slice gap | user defined | user defined | user defined | user defined | user defined | — | — | — |
| gap (mm) | (20) 10 | 0 | 0 | 0 | 0 | — | — | — |
| Slice orientation | sagittal, coronal, (18) transverse | transverse | transverse | transverse | transverse | sagittal | sagittal | sagittal |
| Fold-over direction | AP, (19) RL | RL | RL | RL | AP | AP | AP | AP |
| Fat shift direction | (2) F, (18) P | P | P | P | P | F | F | F |
| radial axis | AP, RL, AP, (17) RL | — | — | — | — | — | — | — |
| radial angle (deg) | (20) 0 | — | — | — | — | — | — | — |
| Minimum number of packages | — | 1 | 1 | 3 | 1 | — | — | — |
| Slice scan order | default | default | default | interleaved | default | — | — | — |
| Stack scan order | ascend | — | — | — | — | — | — | — |
| Multi-chunk | — | — | — | — | — | no | no | no |
| O-MAR | — | no | no | no | — | — | no | — |
| Move table per stack | no | — | — | — | — | — | — | — |
| Large table movement | no | no | no | no | no | no | no | no |
| Stack alignment | no | — | — | — | — | — | — | — |
| Stack sort order | no | — | — | — | — | — | — | — |
| PlanAlign | no | no | no | no | no | no | no | no |
| REST slabs | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| orientation | — | — | — | — | transverse | — | — | — |
| Patient position | head first | head first | head first | head first | head first | head first | head first | head first |
| Patient body position | head first | head first | head first | head first | head first | head first | head first | head first |
| Patient orientation | supine | supine | supine | supine | supine | supine | supine | supine |
| Patient body orientation | supine | supine | supine | supine | supine | supine | supine | supine |
Contrast
| Scan Description | SurveyBrain | AXIALT1 +C | AXIALT2 Fat Sat | AXIALT2 FLAIR +C | SourceDTI | SAGITTAL3D T1 | SAGITTAL3D T2 FLAIR | SAGITTAL3D T1 +C | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Scan type | Imaging | Imaging | Imaging | Imaging | Imaging | Imaging | Imaging | Imaging | Scan type | — |
| Scan mode | M2D | MS | MS | MS | MS | 3D | 3D | 3D | Scan mode | — |
| Modified SE | — | no | no | — | no | — | — | — | Modified SE | — |
| 3D non-selective | — | — | — | — | — | no | — | no | 3D non-selective | — |
| Contrast enhancement | T1 | — | — | — | — | T1 | — | T1 | Contrast enhancement | — |
| Acquisition mode | cartesian | cartesian | cartesian | cartesian | cartesian | cartesian | cartesian | cartesian | Acquisition mode | — |
| Fast Imaging mode | TFE | none | TSE | TSE | EPI | TFE | TSE | TFE | Fast Imaging mode | — |
| 3D VIEW | — | — | — | — | — | — | no | — | 3D VIEW | — |
| TFE factor | 42 | — | — | — | — | 220 | — | 220 | TFE factor | — |
| TSE factor | — | — | 15 | 21 | — | — | 110 | — | TSE factor | — |
| 3D non-selective | — | — | — | — | — | no | — | no | 3D non-selective | — |
| Echoes | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | Echoes | — |
| TE | shortest | user defined | user defined | user defined | shortest | shortest | shortest | shortest | TE | — |
| Flip angle (deg) | 20 | 90 | 90 | — | 90 | 8 | — | 8 | Flip angle (deg) | — |
| Refocusing control | — | — | constant | constant | — | — | constant | — | Refocusing control | — |
| TR | user defined | range | user defined | user defined | shortest | shortest | user defined | shortest | TR | — |
| Halfscan | no | no | no | no | yes | no | — | no | Halfscan | — |
| Water-fat shift | maximum | maximum | maximum | user defined | minimum | maximum | maximum | maximum | Water-fat shift | — |
| IR delay (ms) | — | — | — | 2800 | — | — | 2400 | — | IR delay (ms) | — |
| RF Shims | — | — | — | — | fixed | — | — | — | RF Shims | — |
| Shim | — | default | default | default | PB-volume | auto | default | auto | Shim | — |
| ShimAlign | — | — | — | — | no | — | — | — | ShimAlign | — |
| mDIXON | no | no | no | no | no | no | no | no | mDIXON | — |
| Fat suppression | no | no | SPAIR | no | SPIR | no | SPAIR | no | Fat suppression | — |
| Grad Rev Fat suppr | — | — | — | — | no | — | — | — | Grad Rev Fat suppr | — |
| Water suppression | no | no | no | no | no | no | no | no | Water suppression | — |
| TFE prepulse | invert | — | — | — | — | invert | — | invert | TFE prepulse | — |
| BB pulse | — | no | no | no | no | — | no | — | BB pulse | — |
| MTC | no | no | no | no | no | no | no | no | MTC | — |
| Diffusion mode | no | no | no | no | DTI | no | no | no | Diffusion mode | — |
| T1 mapping | no | no | no | no | no | no | no | no | T1 mapping | — |
| SAR mode | high | high | high | high | high | high | high | high | SAR mode | — |
| B1 mode | default | default | default | default | default | default | default | default | B1 mode | — |
| SAR allow first level | yes | yes | yes | yes | yes | yes | yes | yes | SAR allow first level | — |
| PNS mode | low | high | low | low | high | moderate | high | moderate | PNS mode | — |
| Gradient mode | regular | maximum | default | default | maximum | default | maximum | default | Gradient mode | — |
| SofTone mode | no | no | user defined | user defined | no | no | no | no | SofTone mode | — |
Motion
| Scan Description | Survey Brain |
AXIAL T1 +C |
AXIAL T2 Fat Sat |
AXIAL T2 FLAIR +C |
Source DTI |
SAGITTAL 3D T1 |
SAGITTAL 3D T2 FLAIR |
SAGITTAL 3D T1 +C |
|---|---|---|---|---|---|---|---|---|
| Cardiac synchronization | no | no | no | no | no | no | no | no |
| Respiratory compensation | no | no | no | no | no | no | no | no |
| Navigator respiratory comp | no | no | no | no | no | no | no | no |
| Flow compensation | no | yes | no | no | no | no | sensitized | no |
| fMRI echo stabilisation | no | — | — | — | — | no | — | no |
| Temporal slice spacing | — | default | default | — | default | — | — | — |
| Motion smoothing | — | — | no | no | — | — | no | — |
| NSA | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| SMART | — | no | — | — | — | — | — | — |
| MRE enable | no | no | no | no | no | no | no | no |
Dynamic Angio
| Scan Description | Survey Brain |
AXIAL T1 +C |
AXIAL T2 Fat Sat |
AXIAL T2 FLAIR +C |
Source DTI |
SAGITTAL 3D T1 |
SAGITTAL 3D T2 FLAIR |
SAGITTAL 3D T1 +C |
|---|---|---|---|---|---|---|---|---|
| Angio / Contrast enh. | no | — | — | — | — | no | — | no |
| Quantitative flow | no | — | — | — | — | no | — | no |
| CENTRA | — | — | — | — | — | no | no | no |
| Manual start | no | no | no | no | no | no | no | no |
| Dynamic study | no | no | no | no | no | no | no | no |
| dyn stabilization | — | — | — | — | regular | — | — | — |
| Arterial Spin labeling | no | no | no | no | no | no | no | no |
Post Processing
| Scan Description | Survey Brain |
AXIAL T1 +C |
AXIAL T2 Fat Sat |
AXIAL T2 FLAIR +C |
Source DTI |
SAGITTAL 3D T1 |
SAGITTAL 3D T2 FLAIR |
SAGITTAL 3D T1 +C |
|---|---|---|---|---|---|---|---|---|
| Preparation phases | — | auto | auto | auto | auto | auto | auto | auto |
| Interactive F0 | no | no | no | no | no | no | no | no |
| Quick Survey | default | default | default | default | default | default | default | default |
| B0 field map | no | no | no | no | no | no | no | no |
| MIP/MPR | no | no | no | no | no | no | no | no |
| SWIp | no | — | — | — | — | no | — | no |
| Images | M, (3) no | M, (3) no | M, (3) no | M, (3) no | M, (3) no | M, (3) no | M, (3) no | M, (3) no |
| Autoview image | M | M | M | M | M | M | M | M |
| Calculated images | (4) no | (4) no | (4) no | — | (4) no | (4) no | — | (4) no |
| Reference tissue | White matter | Grey matter | Grey matter | White matter | Grey matter | White matter | Grey matter | White matter |
| Recon compression | No | No | No | No | No | No | No | No |
| Preset window contrast | soft | soft | soft | soft | soft | soft | soft | soft |
| Reconstruction mode | immediate | real time | real time | real time | immediate | immediate | real time | immediate |
| Save raw data | no | no | no | no | no | no | no | no |
| Hardcopy protocol | no | no | no | no | no | no | no | no |
| Image filter | system default | system default | system default | system default | system default | system default | system default | system default |
| Uniformity correction | no | no | no | no | no | no | no | no |
| Geometry correction | default | default | default | default | default | default | default | default |
| Elliptical k-space shutter | — | — | — | — | — | default | default | default |
| EPI geometry correction | — | — | — | — | no | — | — | — |
| IF_info_seperator | — | 1634755923 | 0 | 0 | 0 | 1634755923 | 1634755923 | 1634755923 |