Prostate 3.0T

GE Healthcare – MR Gadopiclenol (VUEWAY®) Protocols

Instructions: • Small FOV: Pelvic side wall to acetabulum; Oblique axis refers to the prostate
• For metal artifacts consider 1.5T, reduced FOV multishot DWI, changing readout direction
• Antiperistalsis: Immediately before motion sensitive pulse sequences 0.6-1 mg glucagon IV; or 25-30 min before motion sensitive pulse sequences glucagon 0.6-1 mg IM or anticholinergic medication such as 0.25 mg hyoscyamine sulfate sublingual or hyoscine butylbromide (Buscopan) 20 mg or higher dose IM (currently not available in the US)
Common Indications: Suspected or known prostate cancer
Position: Supine
Coil: 32 channel Torso, GEMS Body array, or Air coil
Landmark: Iliac Crest

Contrast Agent	Dose				Injection Rate		Dose Timing Method and Scan Delay
Gadopiclenol (VUEWAY)	0.05 mmol/kg up to a calculated volume of 10 mL				2 mL/sec		Scan Mask, scan will pause, inject and scan at the same time If DISCO not available, use SPGR Mph Optional sequence
Saline Flush	50 mL				2 mL/sec		Immediately following gadolinium
Comments	—	—	—	Consider DWI FOCUS if available	—	Consider DWI FOCUS if available	OPTIONAL: Pelvic Survey 4 cm above bifurcation through symphysis	Pre breath held	Dynamic with <15 sec temp resolution for 2 min+	Postcontrast Pelvis Survey 4 cm above bifurcation through symphysis breath held	Optional: Dynamic SPGR	For radiation planning: consider 3D T2, consider using HyperSense for 3D T2

Scan Description	3PL LOCALIZER SSFSE	SAGITTAL T2	OBLIQUE AXIAL T2	Optional: OBLIQUE AXIAL DWI	OBLIQUE CORONAL T2	OBLIQUE AXIAL DWI Hi B Val	Optional: AXIAL T2 Fat Sat	AXIAL T1 LAVA-Flex	AXIAL T1 DISCO	AXIAL T1 LAVA-Flex	AXIAL SPGR Special Fat	AXIAL T2 CUBE
			View Image			View Image			View Image
Mode	2D	2D	2D	2D	2D	2D	2D	3D	3D	3D	3D	3D
Pulse Sequence	SSFSE	FRFSE-XL	FRFSE-XL	EPI-DIFF	FRFSE-XL	EPI-DIFF	FRFSE-XL	3D LAVA-Flex	3D DISCO	3D LAVA-Flex	3D FAST TOF SPGR	CUBE T2
Imaging Options	EDR, SEQ, ARC, SS, FAST	FC, TRf, FAST, FR	FC, TRf, FAST, FR	EPI, DIFF, ASSET, 1 Shot	FC, NPW, TRf, FAST, FR	EPI, DIFF, ASSET, 1 Shot	FC, TRf, FAST, FR	EDR, ZIP512, ZIP2, ARC, FAST	EDR, ZIP512, ZIP2, ARC, Mph, FAST	EDR, ZIP512, ZIP2, ARC, FAST	ZIP512,ZIP2, FAST	EDR, FAST, FR, ZIP512, ZIP2, ARC

Scan Description	3PL LOCALIZER SSFSE	SAGITTAL T2	OBLIQUE AXIAL T2	Optional: OBLIQUE AXIAL DWI	OBLIQUE CORONAL T2	OBLIQUE AXIAL DWI Hi B Val	Optional: AXIAL T2 Fat Sat	AXIAL T1 LAVA-Flex	AXIAL T1 DISCO	AXIAL T1 LAVA-Flex	AXIAL SPGR Special Fat	AXIAL T2 CUBE

TE	90	125	125	Min	125	Min	90	Min	Min	Min	Min Full	90
TR	Min	3400	3500	6000	3500	6000	3500	Def	Def	Def	Def	2500
Flip Angle	—	—	—	—	—	—	—	15	15	15	12	—
ETL	—	23	23	—	23	—	21	—	—	—	InvPrep TI Auto	120
Bandwidth	83	62	62	—	62	—	41	143	143	143	62	62
SAT	—	—	—	—	—	—	Fat Sat	—	—	—	Special Fat Sat	—

Scan Description	3PL LOCALIZER SSFSE	SAGITTAL T2	OBLIQUE AXIAL T2	Optional: OBLIQUE AXIAL DWI	OBLIQUE CORONAL T2	OBLIQUE AXIAL DWI Hi B Val	Optional: AXIAL T2 Fat Sat	AXIAL T1 LAVA-Flex	AXIAL T1 DISCO	AXIAL T1 LAVA-Flex	AXIAL SPGR Special Fat	AXIAL T2 CUBE

MATRIX freq	288	320	320	192	320	192	320	256	224	264	256	256
MATRIX phase	192	224	256	192	224	192	192	224	200	224	160	256
NEX	1	2	2	—	2	—	2	1	1	1	1	1
Phase FOV	1	0.9	0.9	1	1	1	0.8	1	1	1	0.8	1
Freq Direction	—	S/I	R/L	R/L	S/I	R/L	R/L	R/L	R/L	R/L	R/L	R/L
Accel	Ph 2	—	—	—	—	—	—	Ph 2, Sl 2	Ph 1.5, Sl 1.5	Ph 2, Sl 2	—	Ph 2, Sl 2
User CV	1, 240, 1	—	—	Ramp samp 1 Flair Inv 0 Grad opt 1	—	Ramp samp 1 Flair Inv 0 Grad opt 1	Fat Sat eff 1	Min ph os 24 Min sls os 24 Turbo ARC 1	Turbo Mode	Min ph os 24 Min sls os 24 Turbo ARC 1	Turbo 2 Centric 1	—
Other	—	—	—	DWI b val 0-50 Nex 6 Diff Dir TETRA b val 500-800 Nex 6 Opt TE On	—	DWI b val 0-50 Nex 6 Diff Dir TETRA b val 1200-1500 Nex 6 Opt TE On	—	—	25 Phases	—	9 Phases Delay Min Auto Subtract (1 Ph) Collapse off Proj 0	—

Scan Description	3PL LOCALIZER SSFSE	SAGITTAL T2	OBLIQUE AXIAL T2	Optional: OBLIQUE AXIAL DWI	OBLIQUE CORONAL T2	OBLIQUE AXIAL DWI Hi B Val	Optional: AXIAL T2 Fat Sat	AXIAL T1 LAVA-Flex	AXIAL T1 DISCO	AXIAL T1 LAVA-Flex	AXIAL SPGR Special Fat	AXIAL T2 CUBE

FOV	48	26 x 21	26 x 21	30	26 x 26	30	34 x 27	26 x 26	26 x 26	38 x 38	28 x 22	26
Slice Thickness	8	2.4	2.4	4	2.4	4	5	2.6	2.6	3.6	3	1.8
Spacing	0	0.2	0.2	0.5	0.2	0.5	0	0	0	0	0	0
Number of Slices	25	PRN	PRN	30 Slices	PRN	30 Slices	PRN	30 Locs PRN	30 Locs PRN	100 Locs PRN	38 Locs	—
Approx. Scan Time	0:34	4:00 ±	4:00 ±	4:00 ±	4:00 ±	4:00 ±	4:00 ±	0:23 ±	3:30	0:23 ±	4:00	5:00 ±