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Prostate Cancer 3T

Siemens Healthineers – MR Gadopiclenol (VUEWAY®) Protocols

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Instructions And Patient Preparation

Instructions
• Have patient evacuate rectum/rectal gas prior to scan if possible
• Optional: Patient could take a Fleet enema prior to appointment
• NPO for 4 hours prior to study recommended (reduces bowel motion)
• Cover prostate and seminal vesicles
• Endo-Rectal coil not necessary for this protocol particularly with 3T, scan on 3T if possible
Common Indications
Elevated prostate-specific antigen (PSA), palpable prostate nodule, active surveillance
Position
Supine; Head or Feet first
Coil
Body Array (anterior); Spine Array (posterior)
Landmark
Center of coil; below belly button; adjust after LOC using ISO mode imaging

Contrast Agent Parameters

Contrast Agent Dose Injection Rate Dose Timing Method and Scan Delay
Gadopiclenol (VUEWAY) 0.05 mmol/kg 4 mL/sec Perfusion: Start scan, wait 9 sec, inject contrast
Saline Flush >20 mL 4 mL/sec 9 sec injection delay
Comments • Report agent administered and dose
• Use minimal dose for patients with a GFR <30 mL/sec

Imaging Parameters

Scan Description 3 PLANE
HASTE
LOCALIZER
SAGITTAL
T2
AXIAL
T2 TSE
DWI
b50
1000
1600
CALC2000
CORONAL
T2
AXIAL
T1
AXIAL
3D In-Out-
of-Phase
AXIAL
T1 TWIST
TRA DYN Pre
T1 TWIST
Perfusion
AXIAL
VIBE Post
Pelvis
    View Image View Image View Image View Image   View Image View Image View Image View Image
Sequence Name h tse tse epse tse tse fl fldyn fldyn fl
Dimension 2D 2D 2D — 2D 2D 3D 3D 3D 3D
Acceleration mode GRAPPA GRAPPA GRAPPA GRAPPA GRAPPA GRAPPA CAIPIRINHA GRAPPA GRAPPA CAIPIRINHA
Acceleration Factor PE 2 2 2 2 2 2 2 2 2 2
Acceleration Factor 3D — — — — — — 2 1 1 2

Scan Parameters

Scan Description 3 PLANE
HASTE
LOCALIZER
SAGITTAL
T2
AXIAL
T2 TSE
DWI
b50
1000
1600
CALC2000
CORONAL
T2
AXIAL
T1
AXIAL
3D In-Out-
of-Phase
AXIAL
T1 TWIST
TRA DYN Pre
T1 TWIST
Perfusion
AXIAL
VIBE Post
Pelvis
                     
TR 1000 ms 4500 ms 5000 ms 9400 ms 7000 ms 600 ms 4.2 ms 4.95 ms 4.95 ms 3.3 ms
TE 117 ms 121 ms 121 ms 54 ms 118 ms 10 ms 1: 1.29 ms
2: 2.51 ms
1.92 ms 1.92 ms 1.60 ms
Flip Angle 105 deg 160 deg 160 deg — 160 deg 160 deg 9 deg 12 deg 12 deg 10 deg
Turbo Factor 256 27 26 — 25 3 — — — —
Bandwidth 698 Hz/Px 200 Hz/Px 200 Hz/Px 1924 Hz/Px 252 Hz/Px 201 Hz/Px 1040 Hz/Px 260 Hz/Px 260 Hz/Px 650 Hz/Px
Fat-Water Contrast Standard Standard Standard Fat Saturation Standard Standard Standard Standard Standard Fast Fat Saturation
Fat Saturation — — — Strong — — — — — —
Gradient Mode Fast Fast Fast Fast Fast Performance Fast Fast Fast Fast
RF Pulse Type Normal Normal Normal Normal Normal Low SAR Fast Normal Normal Fast
Asymmetric Echo — — — — — — Off Weak Weak Off

Acquisition Parameters

Scan Description 3 PLANE
HASTE
LOCALIZER
SAGITTAL
T2
AXIAL
T2 TSE
DWI
b50
1000
1600
CALC2000
CORONAL
T2
AXIAL
T1
AXIAL
3D In-Out-
of-Phase
AXIAL
T1 TWIST
TRA DYN Pre
T1 TWIST
Perfusion
AXIAL
VIBE Post
Pelvis
                     
Base Resolution 256 320 320 100 320 256 320 192 192 320
Phase Resolution 100% 80% 100% 100% 80% 75% 75% 80% 80% 75%
Slice Resolution — — — — — — 57% 75% 80% 61%
Averages 1 2 2 1, 4, 5 2 1 1 — — 1
Concatenations 1 2 2 1 1 3 1 — — 1
b-value >= — — — — — — 0 s/mm2
50 s/mm2
1000 s/mm2
1600 s/mm2
— — —
FoV Read 380 mm 180 mm 180 mm 240 mm 190 mm 180 mm 380 mm 240 mm 240 mm 380 mm
FoV Phase 100% 100% 100% 100% 100% 100% 81% 100% 100% 81%
Phase Encoding Dir. R >> L H >> F R >> L A >> P F >> H R >> L A >> P — — A >> P
Slice Oversampling — — — — — — 36% — 33% 27%
Phase Partial Fourier 4/8 Off Off Of Off Off Off Off Off Off
Slice Partial Fourier — — — — None None 7/8 Off Off 6/8
Flow Compensation None None None — — — — — — —

Scanning Range

Scan Description 3 PLANE
HASTE
LOCALIZER
SAGITTAL
T2
AXIAL
T2 TSE
DWI
b50
1000
1600
CALC2000
CORONAL
T2
AXIAL
T1
AXIAL
3D In-Out-
of-Phase
AXIAL
T1 TWIST
TRA DYN Pre
T1 TWIST
Perfusion
AXIAL
VIBE Post
Pelvis
                     
Elliptical Filter Off Off Off Off Off Off Off Off Off Off
Normalize Prescan Prescan Prescan Off Prescan Prescan Prescan Off Off Prescan
Distortion Correction 2D 2D 2D 2D 2D 2D 2D 2D 2D 2D
Slice Thickness 6.0 mm 3.0 mm 3.0 mm 3.0 mm 3.0 mm 3.0 mm 3.0 mm 3.0 mm 3.0 mm 3.0 mm
Distance Factor 175% 0% 0% 0% 0% 0% 20% — — 20%
Slices 13 Slices 30 Slices 36 Slices 40 Slices 27 Slices 36 Slices 88 Slices
per Slab
24 Slices
per Slab
24 Slices
per Slab
88 Slices
per Slab
Time of Acquisition 35 sec 2:53 min 4:32 min 6:46 min 2:29 min 2:06 min 19 sec 30 sec 4:37 min 13 sec