{"id":4512,"date":"2025-10-31T16:18:26","date_gmt":"2025-10-31T16:18:26","guid":{"rendered":"https:\/\/protocols.nwforums.com\/index.php\/multiple-sclerosis-brain-3-0t\/"},"modified":"2026-01-07T20:12:49","modified_gmt":"2026-01-07T20:12:49","slug":"multiple-sclerosis-brain-3-0t","status":"publish","type":"page","link":"https:\/\/protocols.nwforums.com\/index.php\/multiple-sclerosis-brain-3-0t\/","title":{"rendered":"Multiple Sclerosis Brain 3.0T"},"content":{"rendered":"<div style=\"justify-content: space-between;align-items: flex-start;margin-bottom: 2rem;flex-wrap: wrap;gap: 1rem\">\n<div>\n<\/div>\n<div id=\"protocol-actions\" style=\"gap: 0.75rem;align-items: center;flex-shrink: 0\">\n<a href=\"\/wp-content\/uploads\/2025\/protocols\/GE_CNS3T_MSBrain.pdf?v=20261005\" target=\"_blank\" style=\"color: white;background: linear-gradient(135deg, #0066cc, #00a8cc);padding: 8px 20px;border-radius: 6px;font-weight: 600;text-decoration: none\">Print<\/a><\/p>\n<\/div>\n<\/div>\n<section>\n<h3>Instructions And Patient Preparation<\/h3>\n<dl>\n<dt>Instructions<\/dt>\n<dd>&#8226; Exam consists of a high resolution Sagittal FLAIR sequence to visualize the corpus callosum<br \/>&#8226; This exam is performed in addition to a brain MRI<br \/>&#8226; Contrast is used for most adult examinations to evaluate for active demyelination<\/dd>\n<dt>Position<\/dt>\n<dd>Supine, head first<\/dd>\n<dt>Coil<\/dt>\n<dd>Head, HNU (Head 24 selected if possible)<\/dd>\n<dt>Landmark<\/dt>\n<dd>Glabella or chin<\/dd>\n<\/dl>\n<\/section>\n<section>\n<h3>Contrast Agent Parameters<\/h3>\n<table style=\"border-collapse: collapse;width: 100%\">\n<thead style=\"border: 1px solid #999;padding: 8px\">\n<tr>\n<th colspan=\"1\" style=\"border: 1px solid #999;padding: 8px\">Contrast Agent<\/th>\n<th colspan=\"3\" style=\"border: 1px solid #999;padding: 8px\">Dose<\/th>\n<th colspan=\"6\" style=\"border: 1px solid #999;padding: 8px\">Injection Rate<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #ccc;padding: 6px\">Gadopiclenol (VUEWAY)<\/td>\n<td colspan=\"3\" style=\"border: 1px solid #ccc;padding: 6px\">0.05 mmol\/kg up to a calculated volume of 10 mL<\/td>\n<td colspan=\"6\" style=\"border: 1px solid #ccc;padding: 6px\">Hand Bolus<br \/>Perfusion-weighted imaging (PWI), injector at 4-5 mL\/sec<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ccc;padding: 6px\">Saline Flush<\/td>\n<td colspan=\"3\" style=\"border: 1px solid #ccc;padding: 6px\">10-20 mL<\/td>\n<td colspan=\"6\" style=\"border: 1px solid #ccc;padding: 6px\">Hand Flush<\/td>\n<\/tr>\n<\/tbody>\n<tfoot>\n<tr>\n<td style=\"background: #fff;color: #000;font-weight: bold;padding: 8px;border: 1px solid #ccc\">Comments<\/td>\n<td colspan=\"1\" style=\"padding: 8px;border: 1px solid #ccc;text-align: center;vertical-align: middle\">&#8226; Report agent administered and dose<br \/>&#8226; Consider MPR 3 mm recons of all 3D sequences in all non-acquired planes<\/td>\n<\/tr>\n<\/tfoot>\n<\/table>\n<\/section>\n<section>\n<h3>Imaging Parameters<\/h3>\n<table>\n<thead>\n<tr>\n<th>Scan Description<\/th>\n<th>3PL<br \/>LOCALIZER<\/th>\n<th>SAGITTAL<br \/>T1 FLAIR<\/th>\n<th>AXIAL <br \/>T2 FS FSE<\/th>\n<th>AXIAL <br \/>T1 3D BRAVO<\/th>\n<th>AXIAL <br \/>DWI<\/th>\n<th>AXIAL <br \/>T2* GRE<\/th>\n<th>Post<br \/>SAGITTAL <br \/>T2 FLAIR CUBE<\/th>\n<th>Post<br \/>AXIAL <br \/>T1 3D BRAVO<\/th>\n<th>Post<br \/>CORONAL<br \/>T1 3D CUBE<\/th>\n<\/tr>\n<tr>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>\n<a href=\"javascript:void(0);\" onclick=\"showImageWithCaption('AXIAL DWI', '\/wp-content\/uploads\/2025\/protocols\/MSBRAIN_3T_Ax_DWI.jpg', 'Courtesy of Howard Rowley, MD.', 160, 550); return false;\" style=\"color: white;background: linear-gradient(135deg, #0066cc, #00a8cc);padding: 6px 16px;border-radius: 6px;font-weight: 600;text-decoration: none\">View Image<\/a>\n<\/th>\n<th>&nbsp;<\/th>\n<th>\n<a href=\"javascript:void(0);\" onclick=\"showImageWithCaption('SAGITTAL T2 FLAIR 3D CUBE ', '\/wp-content\/uploads\/2025\/protocols\/MSBrain_3T_3DCubeT2FLAIR.jpg', 'Courtesy of Aaron S. Field, MD, PhD.', 160, 550); return false;\" style=\"color: white;background: linear-gradient(135deg, #0066cc, #00a8cc);padding: 6px 16px;border-radius: 6px;font-weight: 600;text-decoration: none\">View Image<\/a>\n<\/th>\n<th>\n<a href=\"javascript:void(0);\" onclick=\"showImageWithCaption('AXIAL T1 3D BRAVO', '\/wp-content\/uploads\/2025\/protocols\/MSBrain_3T_3DBRAVOT1.jpg', 'Courtesy of Aaron S. Field, MD, PhD.', 160, 550); return false;\" style=\"color: white;background: linear-gradient(135deg, #0066cc, #00a8cc);padding: 6px 16px;border-radius: 6px;font-weight: 600;text-decoration: none\">View Image<\/a>\n<\/th>\n<th>\n<a href=\"javascript:void(0);\" onclick=\"showImageWithCaption('CORONAL T1 3D CUBE', '\/wp-content\/uploads\/2025\/protocols\/MSBrain_3T_3DCubeT1.jpg', 'Courtesy of Aaron S. Field, MD, PhD.', 160, 550); return false;\" style=\"color: white;background: linear-gradient(135deg, #0066cc, #00a8cc);padding: 6px 16px;border-radius: 6px;font-weight: 600;text-decoration: none\">View Image<\/a>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Primary Sequence<\/td>\n<td>Yes<\/td>\n<td>Yes<\/td>\n<td>Yes<\/td>\n<td>Yes<\/td>\n<td>Yes<\/td>\n<td>Yes<\/td>\n<td>Yes<\/td>\n<td>Yes<\/td>\n<td>Yes T1<\/td>\n<\/tr>\n<tr>\n<td>Mode<\/td>\n<td>2D<\/td>\n<td>2D<\/td>\n<td>2D<\/td>\n<td>3D BRAVO<\/td>\n<td>2D<\/td>\n<td>2D<\/td>\n<td>3D<\/td>\n<td>3D BRAVO<\/td>\n<td>3D<\/td>\n<\/tr>\n<tr>\n<td>Pulse Sequence<\/td>\n<td>SSFSE<\/td>\n<td>IR<\/td>\n<td>FRFSE-XL<\/td>\n<td>BRAVO<\/td>\n<td>SE-EPI<\/td>\n<td>GRE<\/td>\n<td>CUBE<\/td>\n<td>BRAVO<\/td>\n<td>CUBE<\/td>\n<\/tr>\n<tr>\n<td>Imaging Options<\/td>\n<td>SEQ, EDR, FAST,<br \/>SS, ARC, TRF<\/td>\n<td>FC, TRF, <br \/>SEQ, FAST<\/td>\n<td>FC, TRF<\/td>\n<td>FAST, IRP, <br \/>ZIP2, ASSET<\/td>\n<td>EPI, DIFF, ASSET<\/td>\n<td>FC<\/td>\n<td>ARC, T2-IRP, <br \/>ZIP2, EDR<\/td>\n<td>FAST, IRP, <br \/>ZIP2, ASSET<\/td>\n<td>EDR, ZIP2, <br \/>ZIP512, FR, ARC<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<section>\n<h3>Scan Parameters<\/h3>\n<table>\n<thead>\n<tr>\n<th>Scan Description<\/th>\n<th>3PL<br \/>LOCALIZER<\/th>\n<th>SAGITTAL<br \/>T1 FLAIR<\/th>\n<th>AXIAL <br \/>T2 FS FSE<\/th>\n<th>AXIAL <br \/>T1 3D BRAVO<\/th>\n<th>AXIAL <br \/>DWI<\/th>\n<th>AXIAL <br \/>T2* GRE<\/th>\n<th>Post<br \/>SAGITTAL <br \/>T2 FLAIR CUBE<\/th>\n<th>Post<br \/>AXIAL <br \/>T1 3D BRAVO<\/th>\n<th>Post<br \/>CORONAL<br \/>T1 3D CUBE<\/th>\n<\/tr>\n<tr>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>TE<\/td>\n<td>80<\/td>\n<td>24<\/td>\n<td>80<\/td>\n<td>&#8213;<\/td>\n<td>Min<\/td>\n<td>25<\/td>\n<td>Fixed with TR<\/td>\n<td>&#8213;<\/td>\n<td>24<\/td>\n<\/tr>\n<tr>\n<td>TR<\/td>\n<td>1000<\/td>\n<td>3500<\/td>\n<td>3500-4250<\/td>\n<td>&#8213;<\/td>\n<td>9000<\/td>\n<td>800<\/td>\n<td>6000<\/td>\n<td>&#8213;<\/td>\n<td>550<\/td>\n<\/tr>\n<tr>\n<td>TI<\/td>\n<td>&#8213;<\/td>\n<td>Auto<\/td>\n<td>&#8213;<\/td>\n<td>450<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>1954<br \/>(Fixed with TR)<\/td>\n<td>450<\/td>\n<td>&#8213;<\/td>\n<\/tr>\n<tr>\n<td>Flip Angle<\/td>\n<td>&#8213;<\/td>\n<td>Auto<\/td>\n<td>Auto<\/td>\n<td>13<\/td>\n<td>&#8213;<\/td>\n<td>20<\/td>\n<td>Auto<\/td>\n<td>13<\/td>\n<td>13<\/td>\n<\/tr>\n<tr>\n<td>ETL<\/td>\n<td>&#8213;<\/td>\n<td>8<\/td>\n<td>19<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>160<\/td>\n<td>&#8213;<\/td>\n<td>24<\/td>\n<\/tr>\n<tr>\n<td>Bandwidth<\/td>\n<td>83<\/td>\n<td>41<\/td>\n<td>41<\/td>\n<td>25<\/td>\n<td>125<\/td>\n<td>31<\/td>\n<td>32<\/td>\n<td>25<\/td>\n<td>62<\/td>\n<\/tr>\n<tr>\n<td>Sat<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>Fat<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>Fat<\/td>\n<td>&#8213;<\/td>\n<td>Fat<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<section>\n<h3>Acquisition Parameters<\/h3>\n<table>\n<thead>\n<tr>\n<th>Scan Description<\/th>\n<th>3PL<br \/>LOCALIZER<\/th>\n<th>SAGITTAL<br \/>T1 FLAIR<\/th>\n<th>AXIAL <br \/>T2 FS FSE<\/th>\n<th>AXIAL <br \/>T1 3D BRAVO<\/th>\n<th>AXIAL <br \/>DWI<\/th>\n<th>AXIAL <br \/>T2* GRE<\/th>\n<th>Post<br \/>SAGITTAL <br \/>T2 FLAIR CUBE<\/th>\n<th>Post<br \/>AXIAL <br \/>T1 3D BRAVO<\/th>\n<th>Post<br \/>CORONAL<br \/>T1 3D CUBE<\/th>\n<\/tr>\n<tr>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>MATRIX freq<\/td>\n<td>256<\/td>\n<td>352<\/td>\n<td>384<\/td>\n<td>256<\/td>\n<td>128<\/td>\n<td>320<\/td>\n<td>256<\/td>\n<td>256<\/td>\n<td>256<\/td>\n<\/tr>\n<tr>\n<td>MATRIX phase<\/td>\n<td>192<\/td>\n<td>224<\/td>\n<td>256<\/td>\n<td>256<\/td>\n<td>128<\/td>\n<td>256<\/td>\n<td>256<\/td>\n<td>256<\/td>\n<td>256<\/td>\n<\/tr>\n<tr>\n<td>NEX<\/td>\n<td>1<\/td>\n<td>2<\/td>\n<td>2<\/td>\n<td>1<\/td>\n<td>1<\/td>\n<td>1<\/td>\n<td>1<\/td>\n<td>1<\/td>\n<td>1<\/td>\n<\/tr>\n<tr>\n<td>Phase FOV<\/td>\n<td>1<\/td>\n<td>1<\/td>\n<td>0.75<\/td>\n<td>&#8213;<\/td>\n<td>1<\/td>\n<td>0.75<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>0.7<\/td>\n<\/tr>\n<tr>\n<td>Freq Direction<\/td>\n<td>Unswap<\/td>\n<td>S\/I<\/td>\n<td>A\/P<\/td>\n<td>A\/P<\/td>\n<td>R\/L<\/td>\n<td>A\/P<\/td>\n<td>S\/I<\/td>\n<td>A\/P<\/td>\n<td>S\/I<\/td>\n<\/tr>\n<tr>\n<td>Image Enhance<\/td>\n<td>&#8213;<\/td>\n<td>PURE<\/td>\n<td>PURE<\/td>\n<td>PURE<\/td>\n<td>PURE<\/td>\n<td>PURE<\/td>\n<td>PURE<\/td>\n<td>PURE<\/td>\n<td>PURE<\/td>\n<\/tr>\n<tr>\n<td>FC Direction<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>Slice<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>Slice<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<\/tr>\n<tr>\n<td>User CV<\/td>\n<td>&#8213;<\/td>\n<td>CV12 1<br \/>CV22 1<\/td>\n<td>&#8213;<\/td>\n<td>ACC=2<\/td>\n<td>DIFF Dir-All<br \/>#T2 images<br \/>1 Nex 1 for T2 B1000\/1 Nex<br \/> OPT TE On<br \/>Dual SE On<br \/>ACC=2<br \/>Ramp Samp 1<br \/>Recon 1 <br \/>Grad OPT 1<\/td>\n<td>&#8213;<\/td>\n<td>ACC=2<br \/>SL=2<\/td>\n<td>ACC=2<\/td>\n<td>CUBE Enh 3 ACC=2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<section>\n<h3>Scanning Range<\/h3>\n<table>\n<thead>\n<tr>\n<th>Scan Description<\/th>\n<th>3PL<br \/>LOCALIZER<\/th>\n<th>SAGITTAL<br \/>T1 FLAIR<\/th>\n<th>AXIAL <br \/>T2 FS FSE<\/th>\n<th>AXIAL <br \/>T1 3D BRAVO<\/th>\n<th>AXIAL <br \/>DWI<\/th>\n<th>AXIAL <br \/>T2* GRE<\/th>\n<th>Post<br \/>SAGITTAL <br \/>T2 FLAIR CUBE<\/th>\n<th>Post<br \/>AXIAL <br \/>T1 3D BRAVO<\/th>\n<th>Post<br \/>CORONAL<br \/>T1 3D CUBE<\/th>\n<\/tr>\n<tr>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<th>&nbsp;<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>FOV<\/td>\n<td>30<\/td>\n<td>24<\/td>\n<td>22<\/td>\n<td>25<\/td>\n<td>24<\/td>\n<td>22<\/td>\n<td>25<\/td>\n<td>25<\/td>\n<td>24<\/td>\n<\/tr>\n<tr>\n<td>Slice Thickness<\/td>\n<td>7<\/td>\n<td>3<\/td>\n<td>4<\/td>\n<td>2.4<\/td>\n<td>5<\/td>\n<td>5<\/td>\n<td>1.6<\/td>\n<td>1.2<\/td>\n<td>1.8<\/td>\n<\/tr>\n<tr>\n<td>Spacing<\/td>\n<td>5<\/td>\n<td>1<\/td>\n<td>1<\/td>\n<td>&#8213;<\/td>\n<td>1<\/td>\n<td>.5<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<td>&#8213;<\/td>\n<\/tr>\n<tr>\n<td>Number of Slices<\/td>\n<td>7-Ax\/Sag\/Cor<\/td>\n<td>&#8213;<\/td>\n<td>24-26<\/td>\n<td>70<\/td>\n<td>24-26<\/td>\n<td>24-26<\/td>\n<td>126<\/td>\n<td>140<\/td>\n<td>112<\/td>\n<\/tr>\n<tr>\n<td>Scan Time<\/td>\n<td>0:18 sec<\/td>\n<td>2-3 min<\/td>\n<td>~2-3 min<\/td>\n<td>2:30 min<\/td>\n<td>0:50 sec<\/td>\n<td>2 min<\/td>\n<td>3-5 min<\/td>\n<td>4 min<\/td>\n<td>3-5 min<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Print Instructions And Patient Preparation Instructions &#8226; Exam consists of a high resolution Sagittal FLAIR sequence to visualize the corpus callosum&#8226; This exam is performed in addition to a brain MRI&#8226; Contrast is used for most adult examinations to evaluate for active demyelination Position Supine, head first Coil Head, HNU (Head 24 selected if possible) [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"categories":[47,48,43],"tags":[],"class_list":["post-4512","page","type-page","status-publish","hentry","category-3-0t","category-brain","category-ge"],"_links":{"self":[{"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/pages\/4512","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/comments?post=4512"}],"version-history":[{"count":1,"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/pages\/4512\/revisions"}],"predecessor-version":[{"id":5587,"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/pages\/4512\/revisions\/5587"}],"wp:attachment":[{"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/media?parent=4512"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/categories?post=4512"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/protocols.nwforums.com\/index.php\/wp-json\/wp\/v2\/tags?post=4512"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}